More safety and better results - benefit from modernized USP methods!

More safety and better results - benefit from modernized USP methods!

September 24, 2018

Metrohm together with USP have started updating numerous wet chemistry methods for pharmaceutical analysis. This newsletter presents some recently modernized methods including an optimized titration method and a new IC method for zinc oxide assay. 

Optimised USP titration method
The optimized USP titration method replaces the visual endpoint detection by automatic potentiometric determination. Users benefit from safer liquid handling and more accurate results. Here are some applications. 

New IC Method recommended
USP has updated the General Chapter <591> «Zinc Determination» monograph to include ion chromatography as the recommended method for measuring zinc oxide assay.
The new IC method is approved by the FDA and benefits users with more ease of use and better data reproducibility.

Antibody products against PEG from Abcam!

Antibody products against PEG from Abcam!

Polyethylene glycol (PEG) is a synthetic polymer composed of repeating ethylene glycol (-CH2-CH2-O-) units. It has low toxicity, is strongly hydrophilic and has a large exclusion volume in aqueous solution. The covalent attachment of PEG (PEGylation) is commonly used to modify a variety of proteins and drugs. PEGylation can offer several benefits including decreased immunogenicity, increased bioavailability, and optimized pharmacokinetics5.

 

 

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