CALR: the new biomarker for myeloproliferative neoplasm (MPN) research

CALR: the new biomarker for myeloproliferative neoplasm (MPN) research

Anatomy - Pathology

March 21, 2017

Polycythemia vera, essential thrombocythemia and primary myelofibrosis, the three major forms of MPN, are most often associated with Janus kinase 2 (JAK2) mutations. However, a large subset of MPN are JAK2 V617F-negative.

Two large scale studies on MPN showed that many of the JAK2 V617F-negative MPNs were positive for both somatic Type I and Type 2 mutations in calreticulin (CALR).

How can you reliably detect somatic mutations in exon 9 of the CALR gene? Find out now!

 

 

 

Choose the right ELISA kit with Abcam!

Choose the right ELISA kit with Abcam!

Anatomy - Pathology

Careful evaluation of assay performance is an important first step in choosing a new ELISA kit. In fact, when using an ELISA kit, you want specific, accurate, sensitive, and reproducible results. To be sure your kit can deliver this, it’s important to have access to the validation data.

 

 

April 04, 2019 More +
Are you ready for Covid-19 Vaccine?

Are you ready for Covid-19 Vaccine?

Anatomy - Pathology

The first COVID-19 vaccines are due to reach Lebanon in a matter of weeks and they require storage in Ultra-Low-Temperature Freezers to maintain safety and efficiency.

February 05, 2021 More +
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