CALR: the new biomarker for myeloproliferative neoplasm (MPN) research

CALR: the new biomarker for myeloproliferative neoplasm (MPN) research

Anatomy - Pathology

March 21, 2017

Polycythemia vera, essential thrombocythemia and primary myelofibrosis, the three major forms of MPN, are most often associated with Janus kinase 2 (JAK2) mutations. However, a large subset of MPN are JAK2 V617F-negative.

Two large scale studies on MPN showed that many of the JAK2 V617F-negative MPNs were positive for both somatic Type I and Type 2 mutations in calreticulin (CALR).

How can you reliably detect somatic mutations in exon 9 of the CALR gene? Find out now!

 

 

 

Enrich and detect CTCs of prostate cancer from blood

Enrich and detect CTCs of prostate cancer from blood

Anatomy - Pathology

Circulating tumor cells (CTCs) constitute a useful approach for personalized medicine. In prostate cancer, the expression of three tumor-associated transcripts, prostate-specific membrane antigen (PSMA), prostate-specific antigen (PSA) and epidermal growth factor receptor (EGFR), are often altered and used as biomarkers.

March 01, 2017 More +
New TP53 MASTR

New TP53 MASTR

Anatomy - Pathology

Multiplicom is pleased to announce the release of the TP53 MASTR molecular assay for the identification of mutations in the entire coding region of TP53.




September 29, 2015 More +
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