CALR: the new biomarker for myeloproliferative neoplasm (MPN) research

CALR: the new biomarker for myeloproliferative neoplasm (MPN) research

March 21, 2017

Polycythemia vera, essential thrombocythemia and primary myelofibrosis, the three major forms of MPN, are most often associated with Janus kinase 2 (JAK2) mutations. However, a large subset of MPN are JAK2 V617F-negative.

Two large scale studies on MPN showed that many of the JAK2 V617F-negative MPNs were positive for both somatic Type I and Type 2 mutations in calreticulin (CALR).

How can you reliably detect somatic mutations in exon 9 of the CALR gene? Find out now!

 

 

 

NEW single-use data loggers

NEW single-use data loggers

Two new single-use USB data loggers for temperature monitoring of temperature sensitive goods during transport: the EBI 330-T30 and the EBI 330-T85. These loggers are ideal for Pharmaceutical or life science shipments where returning a more expensive multi-use logger after a shipment is difficult. All the user must do is: start the logger and place it with the shipment. The receiver simply plugs it into a computer, and is able to read the automatically generated pdf report. There are no further hassles with returning the logger to the sender!

 

February 01, 2013 More +
How can researchers rapidly resolve the miRNA profile of a single cell?

How can researchers rapidly resolve the miRNA profile of a single cell?

Profiling overall microRNA (miRNA) expression in a heterogeneous sample has been the status quo in miRNA research. Although important for understanding the general biology of a system, bulk analysis doesn’t provide information on the individual influence of cell subtypes. This begs the question: how can we effectively profile miRNA from just one cell?

March 13, 2017 More +
Ready to make an enquiry Call us on: + 961 1 39 66 77
Or email us